Description

Long-lived Proteins in Human Aging and Disease

This authoritative overview of an emerging topic in the molecular life sciences covers all aspects of the aging of

long-lived proteins.

It describes the molecular mechanisms of aging on the protein level, in particular the most common side chain modifications, and includes analytical methods to study protein half-life and the accumulation of modifications. Finally, the impact of protein aging on several age-related diseases in humans is dissected, and their role in limiting human lifespan is discussed.

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